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Updated: Jun 29, 2025

Induction and Assessment of Class Switch Recombination in Purified Murine B Cells
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Published on: August 13, 2010

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免疫球蛋白重链超强增强剂控制了B细胞发育中的类交换机重组

Audrey Dauba1, Emmanuelle Näser1, Dylan Andrieux1

  • 1Institut de Pharmacologie Et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III - Paul Sabatier (UT3), CNRS UMR5089, 205 Route de Narbonne, BP 64182, 31077, Toulouse, France.

Scientific reports
|March 29, 2024
PubMed
概括

3'调节区 (3'RR) 控制成熟B细胞中的抗体类切换 (CSR). 这项研究表明,3'RR对于B细胞发育中的CSR也至关重要,特别是通过hs4增强剂调节开关转录.

关键词:
在IgH位上,IgH位是IgH位.类交换机重组组合类交换机重组早期的B细胞是什么?这是一个超级增强器.切换转录 切换转录

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