TCTP通过细胞间囊泡信号传递来调节基因毒性压力和瘤性

Robert Amson1, Andrea Senff-Ribeiro1, Teele Karafin1

  • 1Institut Gustave Roussy (IGR), Unité Inserm U981, Bâtiment B2M, 114 rue Édouard-Vaillant, 94805, Villejuif, France.

EMBO reports
|March 29, 2024
PubMed
概括

翻译控制的瘤蛋白 (TCTP) 对于癌细胞通过细胞外囊泡 (EV) 进行通信至关重要. 抑制TCTP可降低瘤生长,并改善小鼠的存活率,突出其在瘤信号传递中的作用.

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