机械静脉血栓切除术用于癌症患者的深静脉血栓症:单中心回顾性研究
Riya M Patel1, Koustav Pal1, Syed Hadi Ahmed1
1Department of Interventional Radiology, University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 1471, Houston, TX, 77030-4009, USA.
Cardiovascular and interventional radiology
|March 29, 2024
概括
机械血栓切除术 (MT) 是癌症患者深静脉血栓症 (DVT) 的安全有效治疗方法,成功率高,并发症率低. 在很大一部分患者中发现了瘤血栓,影响了整体存活率.
科学领域:
- 血管外科 血管外科
- 干预性放射学 干预性放射学
- 在瘤学瘤学.
背景情况:
- 静脉血栓塞栓症 (VTE) 对癌症患者的死亡率有显著的贡献.
- 机械血栓切除术 (MT) 提供了一种非血栓溶解的内血管方法来去除血栓.
研究的目的:
- 评估MT在癌症患者下肢深静脉血栓塞 (DVT) 的安全性和有效性.
- 评估临床结果,包括成功率,存活率和并发症.
主要方法:
- 2019年11月至2023年5月,对90名癌症患者进行了单一中心的回顾性研究,这些癌症患者在2019年11月至2023年5月期间接受了下肢DVT的MT.
- 临床成功被定义为维拉拉塔评分下降≥2分;技术成功被定义为恢复静脉流动,残留缺陷最小.
- 二级结局包括无重复干预的生存率和整体生存率.
主要成果:
- 技术和临床成功率分别为81%和87%.
- 一个月,3个月和6个月的重复干预无存活率分别为92%,82%和77%.
- 在18.4%的样本中确定了瘤血栓,与总生存率降低相关 (P=0.012).
结论:
- 机械血栓切除术是一种安全有效的干预措施,用于治疗癌症患者的静脉瘤.
- 瘤血栓的高发病率表明,它是一个比以前怀疑的更常见的发现.
- 在这种患者群体中,MT可以显著降低VTE相关症状.
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