生物检测和实验室结果的解释与检测新生儿与物质暴露相关
Gwendolyn A McMillin1, Anna W Morad2, Jessica M Boyd1
1Department of Pathology and ARUP Laboratories, University of Utah Health, Salt Lake City, UT 84108, United States.
Clinical chemistry
|March 29, 2024
概括
缺乏用于产前物质暴露的标准化生物测试. 目前用于母婴和新生儿检测的方法存在局限性,需要临床背景来准确解释结果.
科学领域:
- 产科和妇科 产科和妇科
- 新生儿医学 新生儿医学
- 临床化学 临床化学
背景情况:
- 在怀孕期间使用物质很普遍,这导致使用生物测试来识别产前暴露.
- 目前对母亲和新生儿物质暴露的生物测试缺乏样本类型,时间,频率和分析物的标准化.
- 现有的检测方法包括免疫测试和质谱,每个测试方法都有临床应用的具体考虑.
研究的目的:
- 审查用于检测产前物质暴露的常见样品类型 (尿液,,带组织).
- 讨论用于物质检测的分析方法,包括免疫检测和质谱.
- 强调对测试利用,解释和指导临床决策的考虑.
主要方法:
- 对用于检测母亲和新生儿物质暴露的常见样品类型的审查.
- 评估分析方法,如免疫试验和质谱学.
- 分析影响测试决策和结果解释的因素.
主要成果:
- 为了检测产前物质暴露,存在各种样本类型和分析方法,每个都有强度和局限性.
- 测试协议中没有标准化,包括样本选择,时间和分析物.
- 可能会出现意想不到的结果,需要仔细的临床解释.
结论:
- 所有用于检测孕妇和新生儿接触物质的方法都有固有的局限性.
- 生物测试的标准化对于关于产前物质暴露的知情临床决策至关重要.
- 生物试验结果必须在临床背景下进行解释,承认假阳性和假阴性的可能性.
相关概念视频
Serum Laboratory Studies, Stool Test, Breath Test
343
Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...
343
Pulmonary Tuberculosis IV
142
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
142


