超声波肌肉评估用于检测炎症性肠道疾病中的sarcopenia:一个前性研究
Giacomo Mulinacci1,2, Lorena Pirola1, Davide Gandola2,3
1Division of Gastroenterology, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy.
United European gastroenterology journal
|March 29, 2024
概括
肌肉超声波可以有效地诊断炎症性肠病 (IBD) 患者的萨尔科佩尼亚. 这种可靠的工具有助于评估肌肉损失,这对于管理IBD和改善患者结果至关重要.
科学领域:
- 医疗成像医学成像
- 胃肠病学 胃肠病学
- 肌肉骨健康 肌肉骨健康
背景情况:
- 在炎症性肠道疾病 (IBD) 患者中,萨科佩尼亚是常见的.
- 它会对手术和治疗结果产生负面影响.
- 需要有效的诊断工具来评估IBD的肌肉质量和功能.
研究的目的:
- 评估肌肉超声波 (US) 作为IBD患者肉症的诊断工具.
- 与生物电阻分析 (BIA) 和磁共振成像 (MRI) 相比,评估US的可靠性和准确性.
主要方法:
- 包括153名患者 (100名培训,53名研究队列).
- 腿直体 (RF),腹直体 (RA) 和双臂肌 (BB) 的肌肉厚度是使用US测量.
- 美国的诊断准确性与IBD患者的BIA和MRI进行了测试.
主要成果:
- 在IBD患者中,肉症的患病率为50%.
- 肌肉美国显示出出色的可靠性 (ICC>0.95) 和良好的诊断准确性 (RA和BB厚度的AUROC 80-85%).
- 超声波肌肉指数 (USMI) 显示AUROC为81%,RA和USMI值与高预测值相关.
结论:
- 肌肉美国是诊断IBD患者的肉症的可靠工具.
- 这一发现对IBD疾病管理有重大影响.
- 建议在更大的队列中进一步验证.
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