现在是时候改变范式了吗? 在遗传性失脂症小组中包含APOE
Hannah E Ison1, Mohammad Mowaswes2, Ronen Durst2
1Stanford Center for Inherited Cardiovascular Disease, Stanford Health Care, Stanford, California, USA.
Journal of genetic counseling
|March 29, 2024
概括
APOE基因变异影响脂质代谢和冠状动脉疾病风险. 尽管与阿尔茨海默氏症有关,但应考虑对遗传性脂质不良症进行APOE的遗传检测.
科学领域:
- 遗传学和心血管疾病
- 脂质新陈代谢研究研究
背景情况:
- 脂蛋白E (ApoE) 对于脂质代谢和恒温至关重要.
- APOE变种与遗传性失脂症和早发性冠状动脉疾病 (CAD) 有关.
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