儿童中轻度慢性胃炎的患病率上升:一个单一中心的经验
Rohit Josyabhatla1, Mary Lauren Wood2, Amber Gafur3
1Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, The University of Texas Health Science Center at Houston, McGovern Medical School, Houston, TX, USA.
儿童慢性胃炎的患病率在十年内显著增加,近年来观察到更高的发病率. 这一趋势凸显了儿童胃肠道健康日益关注的问题.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 胃肠内镜检查 胃肠内镜检查
- 组织病理学 组织病理学
背景情况:
- 上部胃肠内镜是评估儿科胃肠症状的关键诊断工具.
- 儿童慢性胃炎可能导致各种症状,包括腹痛,吐,发育不良和腹.
- 了解儿科胃肠道疾病的趋势对于公共卫生和临床实践至关重要.
研究的目的:
- 在10年的时间内分析儿童上部内镜和组织学发现的趋势.
- 在三个不同的队列中调查儿科患者慢性胃炎的患病率.
- 为了比较胃炎病例和对照病例之间的内镜检测结果.
主要方法:
- 从三个儿科队列 (2011年,2015年,2019年) 上部内镜和组织学数据的回顾性分析.
- 包括579名儿科患者,按队列年分类.
- 评估常见的症状,如腹痛,吐,发育不良和腹.
主要成果:
- 慢性胃炎的组织学证据显著增加,从2011年的29%增加到2019年的68% (P < .001).
- 正常的内镜胃部发现的患病率在病例中较低 (76%) 与对照组 (90%) 相比 (P < .001).
- 随着时间的推移,观察到内镜食道分级的统计学上显著差异 (P = .008).
结论:
- 在过去的十年中,在儿科患者中观察到轻度慢性或非特异性胃炎的患病率显著增加.
- 儿科胃炎的患病率越来越高,因此需要进一步研究其潜在原因和长期影响.
- 这些发现强调了定期进行内镜和组织学评估对于患有相关胃肠道症状的儿童的重要性.
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