结核病和糖尿病患者的营养状况:一项比较观察性研究
Divya Girishbhai Patel1, Tejaswini Baral1, Shilia Jacob Kurian1
1Department of Pharmacy Practice, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka 576104, India.
概括
营养不良对结核病和糖尿病 (TB-DM) 患者产生重大影响,导致病情恶化. 营养支持对这一脆弱人群至关重要,以改善治疗结果并降低死亡风险.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 内分泌学 在内分泌学.
背景情况:
- 印度面临着营养不良 (14%) 和结核病 (26.9万例) 的重大负担.
- 营养不良和糖尿病被确定为结核病感染的主要危险因素.
- 在结核病和糖尿病 (TB-DM) 患者中,营养不良加剧了疾病的严重程度,损害了治疗结果,增加了死亡率.
研究的目的:
- 评估和比较诊断出结核病和糖尿病 (TB-DM) 的患者的营养状况.
- 为了比较结核病-DM患者的营养参数与单独结核病 (TB) 和单独糖尿病 (DM) 患者的营养参数.
主要方法:
- 这是一项对2016年1月至2020年11月期间入院的291名患者的回顾性分析.
- 患者被分为三组:TB-DM,单独的TB和单独的DM (每组97名患者).
- 统计分析,包括单向ANOVA,用于评估血糖和营养参数,p < 0.05被认为是显著的.
主要成果:
- 结核病-糖尿病组的HbA1c平均值最高 (10.47%).
- 71.91%的结核病患者和73.68%的TB-DM患者患有低专蛋白水平,这些患者也表现出高水平的维生素D缺乏症.
- 铁缺乏性贫血的风险增加是由TB-DM组中低MCV和MCH的更高患病率表明的.
结论:
- 这项研究强调了为结核病和糖尿病 (TB-DM) 联合感染的患者整合营养支持策略的关键需求.
- 解决结核病-DM患者的营养不良问题对于改善临床结果和减少相关的发病率和死亡率至关重要.
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