血栓不发的上胃肠道出血的 hemospray 与传统疗法对比:系统性审查和元分析
Mihir P Shah1, Sania Saleem1, Bashar Attar2,3
1Internal Medicine, John H. Stroger, Jr. Hospital of Cook County, Chicago, USA.
Cureus
|March 29, 2024
概括
黑梅斯普雷显著改善了非变节性上部胃肠道出血的初级血液静止. 这项研究发现,在使用Hemospray作为主要治疗时,不会增加再出血,手术或死亡的风险.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 医疗器械 医疗器械
背景情况:
- 黑梅斯普雷 (TC-325) 用于在非水上部胃肠道出血的血液静止.
- 目前的指导方针建议使用Hemospray作为临时或辅助措施.
- 它作为一次性静血模式的有效性需要进一步评估.
研究的目的:
- 系统地审查和元分析Hemospray作为初级静血方法的疗效和安全性.
- 为了比较Hemospray的有效性与标准护理对非的上部胃肠道出血.
主要方法:
- 在MEDLINE,CENTRAL和CINAHL数据库中搜索到2022年8月1日.
- 包括关于Hemospray作为非水上部胃肠道出血的初级静血的原始文章.
- 使用Cochrane偏差风险工具评估研究质量.
主要成果:
- 从303名患者的数据汇总显示,使用Hemospray的初级血液静止的几率显著更高 (OR:3.48,p=0.04).
- 在再出血率上没有发现显著差异 (OR:0.79,p=0.69).
- 在需要手术 (OR:1.62,p=0.54) 或整体死亡率 (OR:1.08,p=0.83) 中没有发现显著差异.
结论:
- 黑梅斯普雷证明了作为一种主要的血液静止方法,在非的上部消化道出血方面具有卓越的疗效.
- 使用Hemospray作为主要治疗方法不会增加再出血,手术或死亡的风险.
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