在使用Poincaré图表的狗中评估心率变化分析的指标
Taichi Kimura1, Shunsuke Shimamura1, Hiroshi Sakaya2
1Laboratory of Small Animal Clinical Medicine, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Izumisano, Osaka, Japan.
Veterinarni medicina
|March 29, 2024
概括
像SD1和SD2这样的Poincaré图表指标可靠地评估狗的自主神经系统功能. 这些定量测量有效地检测药物阻断后抑制的副交感神经活动.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 生理学 生理学 生理学
- 心脏病学 心脏病学
背景情况:
- 通过Poincaré图表进行心率变化 (HRV) 分析,有助于评估自主神经系统 (ANS) 功能.
- 庞卡雷图片指标的定量解释是有争议的,在兽医中仅有有限的验证.
研究的目的:
- 用药理学模型在狗中验证Poincaré图表指标的可靠性.
- 评估特定的定量指标在反映ANS变化的有效性.
主要方法:
- 给四只健康的 beagle 动物注射了 propranolol,atropine 或其组合,以阻止交感性,副交感性或两种 ANS 功能.
- 定量普恩卡雷图谱指标 (SD1,SD2,SD1×SD2,SD1/SD2) 由药物给药前后300次心电图拍数计算出来.
- 进行了统计分析,以确定指标的重大变化.
主要成果:
- SD1,SD2和SD1×SD2在表交友和表交友-表交友封锁后显著下降.
- 在测试条件下,SD1/SD2比率没有显著差异.
- 普恩卡雷图表指标准确地反映了狗的自主神经系统活动中的诱导变化.
结论:
- 定量指标SD1,SD2和SD1×SD2可靠地评估狗的ANS功能.
- 这些指标可以有效地检测压抑的副交感神经活动的状态.
- 卡雷图片分析为兽医自主功能测试提供了有价值的工具.
相关概念视频
01:25Correlation between ECG and Cardiac Cycle
5.1K
The electrical signals recorded on an electrocardiogram (ECG) occur before the mechanical processes of contraction and relaxation during the cardiac cycle.
A cardiac action potential originates in the SA node and spreads throughout the atria and the AV node in approximately 0.03 seconds. This results in the P wave in an ECG and triggers atrial contraction. The action potential is then briefly slowed at the AV node, allowing the atria to contract and fill the ventricles with blood before...
A cardiac action potential originates in the SA node and spreads throughout the atria and the AV node in approximately 0.03 seconds. This results in the P wave in an ECG and triggers atrial contraction. The action potential is then briefly slowed at the AV node, allowing the atria to contract and fill the ventricles with blood before...
5.1K
01:15Receiver Operating Characteristic Plot
154
A ROC (Receiver Operating Characteristic) plot is a graphical tool used to assess the performance of a binary classification model by illustrating the trade-off between sensitivity (true positive rate) and specificity (false positive rate). By plotting sensitivity against 1 - specificity across various threshold settings, the ROC curve shows how well the model distinguishes between classes, with a curve closer to the top-left corner indicating a more accurate model. The area under the ROC curve...
154
01:30Pulse rhythm
795
Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
795