治疗方案复杂性 (MRC-ICU) 用于在COVID-19患者的住院死亡率预测
Hanna Azimi1, Logan Johnson2, Carly Loudermilk2
1Augusta University Medical Center, Augusta, GA, USA.
Hospital pharmacy
|March 29, 2024
概括
药物治疗方案复杂性-重症监护室 (MRC-ICU) 的得分显示了可接受的预测COVID-19在医院死亡率. 然而,顺序性器官衰竭评估 (SOFA) 评分在这个患者群体中是一个更强大的预测指标.
科学领域:
- 关键护理医学 关键护理医学
- 传染性疾病 传染性疾病
- 药物经济学 药物经济学
背景情况:
- 药物治疗方案复杂性-重症监护室 (MRC-ICU) 评分是在COVID-19大流行之前开发的.
- 在新型疾病背景下评估先前存在的评分的有用性对于临床决策至关重要.
研究的目的:
- 评估MRC-ICU得分对COVID-19患者住院死亡率的预测性表现.
- 将MRC-ICU的预测能力与其他已确定的临床严重性得分进行比较.
主要方法:
- 一个单一中心的观察性研究包括从2020年8月到2021年1月的149名COVID-19患者.
- 主要结果是使用48小时MRC-ICU得分的住院死亡率接收器操作特征 (AUROC) 曲线下的区域.
- 后勤回归分析用于预测死亡率和世界卫生组织COVID-19严重程度分类.
主要成果:
- 住院死亡率为36%.
- 在预测死亡率方面,MRC-ICU得分的AUROC为0.71.
- 顺序性器官衰竭评估 (SOFA) 评分 (AUROC 0.81) 和世卫组织严重性分类 (AUROC 0.72) 显示出比MRC-ICU更强大的预测能力.
结论:
- 在MRC-ICU得分证明了可接受的,虽然不是优越的,在COVID-19患者的住院死亡率的预测能力.
- 在这个队列中,SOFA得分成为了住院死亡率的最强有力的预测因素.
关键词:
冠状病毒严重程度得分COVID严重程度得分在 COVID-19 疫情中,关键护理关键护理 关键护理药物治疗方案复杂性 药物治疗方案复杂性质量改善 质量改善序列性器官功能衰竭评估 (SOFA) 是指对器官功能衰竭进行序列性评估.更多相关视频
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