美国老年人中饮食炎症指数和认知障碍之间的关联:一个横截面研究
Yu Zhang1, Yuanyuan Peng2, Wei Deng1
1Chongqing Mental Health Center, Chongqing, China.
Frontiers in aging neuroscience
|March 29, 2024
概括
具有较高炎症潜力的饮食与美国老年人的认知能力下降有关. 这项研究强调了饮食炎症指数 (DII) 与认知障碍之间的关联,表明饮食模式可能会影响大脑健康.
科学领域:
- 营养科学 营养科学
- 神经科学是一个神经科学.
- 流行病学 流行病学
背景情况:
- 炎症与认知障碍 (CI) 有关.
- 饮食显著影响着炎症.
- 关于饮食的炎症潜力和CI的流行病学数据有限.
研究的目的:
- 研究美国老年人饮食炎症指数 (DII) 与认知障碍之间的相关性.
- 探索饮食炎症潜力和认知功能下降之间的关联.
主要方法:
- 国家健康和营养检查调查 (NHANES) 数据 (2011-2014) 的横截面分析.
- 饮食摄入量数据用于计算DII得分,并将参与者分为四分之一.
- 使用CERAD,AFT和DSST评估认知功能;低绩效定义为最低四分位数得分.
主要成果:
- 在AFT (OR 1.15) 和DSST (OR 1.38) 上,在较高的DII得分和较低的认知表现之间发现了显著的正相关性.
- 与最低四分位数相比,DII四分位数最高的个体表现出认知障碍的几率显著增加 (AFT:OR 1.89;DSST:OR 4.30).
- 在DSST上观察到DII和认知衰退之间存在非线性关系.
结论:
- 较高的饮食炎症潜力与美国老年人的认知能力下降有关.
- 这些发现表明饮食,炎症和认知健康之间存在联系.
- 需要进一步研究饮食干预措施以确定因果关系.
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