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创伤性植入性角质炎是由中印度的Schizophyllum commune引起的
Anand Kumar Maurya1, Sweta Kumari1, Karuna Tadepalli1
1Department of Microbiology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, 462020, India.
Medical mycology case reports
|March 29, 2024
概括
经过角膜创伤后发生的Schizophyllum commune引起的严重真菌角膜炎的两例病例导致视力丧失,尽管接受了伏利可纳治疗和治疗性角膜造形术.
科学领域:
- 眼科医生 眼科 眼科
- 菌类学 菌类学是指菌类学.
- 传染性疾病 传染性疾病
背景情况:
- 角膜创伤可能导致严重的感染.
- 真菌角膜炎是一种具有挑战性的眼睛感染,特别是当它是由罕见的真菌引起时.
- 早期诊断和治疗对于治疗真菌角膜炎至关重要.
研究的目的:
- 在角膜创伤后报告两例由Schizophyllum commune引起的真菌角膜炎病例.
- 要突出临床表现,诊断方法和治疗结果.
- 为了强调这种真菌感染的攻击性及其对视力的影响.
主要方法:
- 两名患有角膜创伤和随后的患者的病例介绍.
- 临床检查,包括对缺血细胞的评估.
- 微生物学研究,包括真菌培养和鉴定 (常规和分子方法).
- 用局部和静脉注射沃里科纳进行药理治疗.
- 通过治疗性角质塑造进行手术干预.
主要成果:
- 两名患者在创伤后出现角膜,其中一名患者表现出hypopyon.
- 在真菌培养中发现了Schizophyllum commune.
- 开始治疗沃里康纳,但没有阻止疾病的进展.
- 在这两种情况下都进行了治疗性角膜整形术,但最终失败了.
- 两位患者都在受影响的眼睛中经历了不可逆转的视力损失.
结论:
- 在角膜创伤后,Schizophyllum commune可以引起严重的真菌角膜炎.
- 这种真菌可能对标准的抗真菌疗法,包括沃里可纳,有抗性.
- 积极的手术管理,如治疗性角质整形可能并不总是成功的.
- 性角膜炎,特别是来自罕见生物的性角膜炎,具有显著的视力损失风险.
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