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通过精准医学在极端环境中优化人类性能:从太空飞行到地球上的高性能操作

Michael A Schmidt^1,2, Jeffrey A Jones³, Christopher E Mason⁴

¹Sovaris Aerospace, Boulder, CO, USA.

Cambridge prisms. Precision medicine

|March 29, 2024

概括

精准医学 (PM) 为极端环境中的个人提供量身定制的健康和绩效策略. 通过分析分子数据,PM提供了个性化的对策,以优化高风险操作中的安全和生存.

科学领域:

极端环境生理学极端环境生理学
人类性能优化优化人类性能优化
分子生物学分子生物学

背景情况:

处于极端环境中的个体在接近人类性能极限的范围内运行.
错误影响执行,风险,安全,健康和生存的小幅度.
加强准备,训练,健身和医疗护理至关重要.

研究的目的:

介绍极端环境中精准医学 (PM) 的系统方法.
将临床实践的输入,流程和输出的语境化.
专注于分子动力学,同时承认生理和行为现象型.

主要方法:

对PM的系统方法的概述.
专注于分子动力学和功能性特征分子网络.
展示指导PM应用的原则.

主要成果:

精准医学因分子分析深度而特别适合于极端操作.
PM使得准确的对策能够与个别的表型和环境相匹配.
对分子网络效率的分析显示,增量收益/损失会影响健康和性能.

结论:

对PM的系统方法为极端环境中的临床医生提供了一个框架.
了解分子动力学是优化健康和表现的关键.
突出了分子分析和对策的实际考虑.

关键词:

多种主题的多种主题.药物基因组学药物基因组学精准医学是一门精准医学.预防医学是预防医学.治疗创新治疗创新

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