反流信号评估-10 (RSA-10) 的有效性和可靠性
Jérôme R Lechien1,2,3,4, Lisa G De Marrez4, Camille Finck1,5
1Research Committee of the Young-Otolaryngologists of the International Federations of Oto-rhino-laryngological Societies (YO-IFOS), Paris, France.
The Laryngoscope
|March 29, 2024
概括
反流体信号评估-10 (RSA-10) 有效地记录了喉回流性疾病 (LPRD) 的物理发现. 这种经过验证的工具在识别LPRD方面具有很高的可靠性和准确性,有助于临床诊断.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 胃肠病学 胃肠病学
- 医学诊断 医学诊断 医学诊断
背景情况:
- 喉回流性疾病 (LPRD) 呈现出各种喉和喉症状.
- 对物理发现的准确记录对于LPRD诊断和管理至关重要.
- 现有的评估工具可能缺乏对物理标志的全面验证.
研究的目的:
- 开发和验证反流信号评估-10 (RSA-10) 作为临床仪器.
- 评估RSA-10对LPRD物理发现的可靠性和有效性.
- 为了确定RSA-10的诊断值在识别LPRD.
主要方法:
- RSA-10是在LPRD患者和无症状对照患者身上开发和测试的.
- 评估了内部一致性,测试-重新测试可靠性和评价者之间的可靠性.
- 通过与反流检测得分 (RFS) 的相关性来评估趋同有效性.
- 通过ROC分析分析了对治疗的反应和诊断准确度.
主要成果:
- RSA-10显示出高的内部一致性 (α=0.822) 和测试重试可靠性 (rs=0.725).
- 与对照组相比,患有LPRD的患者的RSA-10得分显著更高 (p=0.001).
- RSA-10分数与RFS有很强的相关性 (rs=0.771) 并显示出足够的评分器间可靠性 (k=0.708).
- 该仪器对治疗有反应,治疗后有显著改善 (p=0.001).
- 一个RSA-10得分>13表示LPRD92.7%的灵敏度和97.3%的特异性.
结论:
- RSA-10是一个可靠和有效的工具,用于记录与LPRD相关的物理发现.
- 它有助于客观地评估LPRD的喉和喉外症状.
- 在临床实践中,RSA-10可以有效地用于LPRD诊断和监测.
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