影响透析患者睡眠质量的危险因素:单中心横截面研究
Yanmei Peng1, Huie Huang1, Yumei Liao1
1Division of Renal Medicine, Peking University Shenzhen Hospital, Peking University, Shenzhen, China.
Medicine
|March 29, 2024
概括
透析患者的睡眠质量差与女性,高血压,,不安腿综合征,抑郁症和高费里水平有关. 解决这些因素对于改善患者的健康和生活质量至关重要.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 睡眠医学 睡眠医学
- 临床研究 临床研究
背景情况:
- 睡眠障碍是透析患者常见的并发症,严重影响他们的整体健康和生活质量.
- 在这个人群中,导致睡眠质量差的特定风险因素仍然不完全理解,需要进一步调查.
研究的目的:
- 确定和分析与接受透析的患者睡眠质量下降相关的关键风险因素.
- 为透析患者对睡眠的多因素影响提供全面的理解.
主要方法:
- 一项涉及260名透析患者的截面研究,从2023年5月至10月进行.
- 数据收集包括详细描述症状和病史的患者问卷,以及来自医疗记录的生物化学参数.
- 使用统计分析,包括单变量和多因素回归,以确定显著的关联.
主要成果:
- 统一分析显示了睡眠质量差与女性性别,初级脏疾病类型,高静脉血压 (SBP),,不安腿综合征 (RLS),焦虑和抑郁之间的关联.
- 与睡眠不良相关的生化指标包括低,低和高费里水平.
- 多因素回归确定了女性性别,,RLS,高SBP,抑郁症和高费里水平作为睡眠质量差的独立预测因素.
结论:
- 女性性别,慢性炎综合征,高SBP,,RLS,情绪低落和费里水平升高是与透析患者睡眠质量差相关的重要因素.
- 针对性干预和个性化护理策略对于改善睡眠质量和改善这一弱势群体患者的治疗结果至关重要.
相关概念视频
Dialysis
307
Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
307
Insufficient Sleep and Sleep Deprivation
141
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
Sleep deprivation is a more severe form of sleep loss...
141
Factors Affecting Renal Clearance: Renal Impairment
91
Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
91
Renal Failure: Dose Adjustments
88
In patients with renal impairment, drugs undergo significant changes in their pharmacokinetics, which require dosage adjustments to ensure safe and effective therapy.
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
88
Restless Leg Syndrome and Night Terrors
175
Restless Leg Syndrome (RLS), also known as Willis-Ekbom disease, is a neurological disorder characterized by an uncontrollable urge to move the legs due to uncomfortable sensations. These sensations typically occur during periods of rest or inactivity, particularly when lying down or sitting, and can severely disrupt sleep.
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
The exact cause of RLS is not fully understood, but it is believed to involve dopamine, a neurotransmitter that helps regulate muscle movement. Imbalances in dopamine levels...
175
Substance Use Disorders Affecting Sleep
166
Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Understanding the concepts of physical dependence,...
166


