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Updated: Jun 29, 2025

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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对全调节器的多种结合模式及其对多巴胺D1受体的调节的计算洞察

Jianfang Chen1, Yuanpeng Song1, Luhan Ma1

  • 1College of Chemistry, Sichuan University, Chengdu, 610064, China.

Computers in biology and medicine
|March 29, 2024
PubMed
概括

多巴胺D1受体 (DRD1) 的阿洛斯特基调制剂表现出多种结合方式. 矛盾的是,最稳定的结合模式产生了最弱的全效应,为药物设计提供了见解.

关键词:
其他模块的模块.绑定模式 绑定模式与G蛋白结合的受体是G蛋白结合的受体.分子动力学模拟模型监管机制 监管机制 监管机制

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