左心房附属体形态和功能与中风和过渡性缺血性发作在心房患者中的关联
Judit Simon1, Jeff M Smit2, Mohammed El Mahdiui2
1MTA-SE Cardiovascular Imaging Research Group, Medical Imaging Centre, Budapest, Hungary.
The American journal of cardiology
|March 29, 2024
概括
在心房患者中,左心房尾功能减弱和天形状增加中风风险. 然而,风的形状可以防止中风/TIA.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 预防中风 预防中风
背景情况:
- 心房动 (AF) 是一种常见的心律失常,与中风风险增加有关.
- 左心房附属体 (LAA) 是AF患者血栓形成的主要来源.
- 了解LAA的结构和功能对于分层中风风险至关重要.
研究的目的:
- 研究左心房附属体 (LAA) 形态和功能与中风/暂时性缺血性发作 (TIA) 在AF患者中发生率之间的相关性.
- 为了确定特定的LAA形状和功能参数,与更高的血栓栓塞事件风险相关.
主要方法:
- 分析了649名AF患者的数据,这些患者接受了导管切除.
- 用心脏计算机断层扫描 (CT) 和食道间心声扫描 (TEE) 来评估LAA的形态和功能.
- LAA形态被分为四种不同的形状:花菜,翅,天和风.
主要成果:
- 降低LAA流速 (≤35.3厘米/秒) 独立地与中风/TIA (OR 2.18) 的更高风险相关.
- "天"的LAA形状也独立地与中风/TIA风险增加有关 (OR 2.69).
- 与"花花"形状相比",风"LAA形态显示出对中风/TIA (OR 0.32) 的保护作用,LAA孔面积和体积显着较小,与"花花"形状相比.
结论:
- 减少LAA功能和"天"LAA形态是AF患者中风/TIA患病率增加的独立预测因素.
- 在这个人群中",风"LAA形态似乎可以防止中风/TIA.
- LAA形态,特别是"风"形状,影响LAA尺寸,可能在中风风险分层中发挥作用.
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