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Updated: Jun 29, 2025

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
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SLC25A3通过限制NLRP3的功能来负面调节NLRP3炎症酶激活

Feng Xiao1, Yaling Jia2, Simeng Zhang3

  • 1Hubei Key Laboratory of Cognitive and Affective Disorders, Institute of Biomedical Sciences, School of Medicine, Jianghan University, Wuhan, China; Department of Urology, The Third Affiliated Hospital of Shenzhen University (Luohu Hospital Group), Shenzhen, China.

The Journal of biological chemistry
|March 29, 2024
PubMed
概括

溶性载体家族25成员3 (SLC25A3) 负调节NLRP3炎症体. 这种线粒体蛋白与NLRP3相互作用,破坏其激活,并为炎症性疾病提供新的治疗点.

关键词:
在NLRP3炎症酶激活过程中,NLRP3在SLC25A3A3中使用.天生的免疫反应.线粒体中的线粒体.热致灭 (pyroptosis) 是一种致的过程.

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