在COVID-19的后急性阶段发生甲状腺功能障碍的风险:香港的一项基于人口的队列研究
David Tak Wai Lui1, Xi Xiong2, Ching-Lung Cheung3
1Department of Medicine, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.
概括
COVID-19幸存者在感染后没有增加甲状腺功能障碍的风险. 这项大型研究发现COVID-19和持续的甲状腺问题之间没有显著的关联,为公众健康提供了令人放心的数据.
科学领域:
- 内分泌学 在内分泌学.
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 在SARS-CoV-2感染后,甲状腺功能障碍的证据有限.
- 评估COVID-19的后急性后果对于了解长期健康影响至关重要.
研究的目的:
- 评估COVID-19后急性阶段发生甲状腺功能障碍的风险.
- 提供关于COVID-19和甲状腺健康之间的关联的数据.
主要方法:
- 追溯性,倾向性得分匹配,基于人口的队列研究.
- 包括84,034名COVID-19幸存者和84,034名来自香港电子医疗记录的匹配对照.
- 随访至2023年1月,使用考克斯回归分析复合甲状腺功能障碍结果.
主要成果:
- 在COVID-19后诊断出甲状腺功能障碍的风险没有显著增加 (HR 1.058,P=.154).
- 没有观察到过高甲状腺症,甲状腺功能低下症,抗甲状腺药物启动,甲状腺素启动或甲状腺炎的风险增加.
- 小组和灵敏度分析证实了这些发现.
结论:
- COVID-19不太可能与甲状腺功能的持续影响有关.
- 这项研究提供了有关COVID-19幸存者的长期甲状腺健康的令人放心的证据.
相关概念视频
01:20Synthesis and Regulation of Thyroid Hormones
4.6K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
4.6K
01:18Functions of Thyroid Hormones
2.7K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
2.7K
01:30Acute Pharyngitis
633
Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
633
01:30Radiological Investigation I: X-ray and CT
237
Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
237
01:13Radiological Investigation III: Pulmonary Angiogram and PET Scan
91
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
91