输血安全:在低收入和中等收入国家和高收入国家报告的反应之间是否存在差异?
Mohamed Amine Hmida1, Sonia Mahjoub1, Leila Ben Hamed2
1Faculty of Medicine of Tunis - University Tunis El Manar, Djebal Lakhdar Street, 1006 Tunis, Tunisia; Hematology Laboratory, La Rabta University Hospital, La Rabta, 1007 Tunis, Tunisia.
概括
低资源国家的输血反应与高收入国家相似,这表明先进技术的影响最小. 然而,在LMICs中,ABO不兼容性仍然较高,因此需要为输血医学人员提供更好的培训.
科学领域:
- 输血医学 输血医学
- 患者安全 患者安全
- 医疗保健的不平等 医疗保健的不平等
背景情况:
- 输血安全可能会受到金融资源的影响,可能会在高收入国家 (HIC) 和中低收入国家 (LMIC) 之间造成差异.
- 之前的研究并没有广泛地比较HIC和LMIC之间的输血反应 (TR) 率.
研究的目的:
- 评估和比较在突尼斯报告的输血反应 (TR) 的频率,一个LMIC,与报告在HIC.
- 评估先进的输血技术对不同经济环境中的安全的影响.
主要方法:
- 输血反应数据是从2015年至2019年期间在突尼斯的输血事件报告 (TIR) 表格中收集的.
- 来自突尼斯的TR数据与来自法国 (ANSM) 和英国 (SHOT) 的数据进行了比较.
主要成果:
- 总体TR发病率为每10万发行的血液成分 (BP) 中的70.6.
- 发烧性非溶血输血反应 (43.7%) 和过敏反应 (35%) 是最常见的TR.
- ABO不兼容性发生在每10万个红细胞 (RBC) 单位中的1.96个,所有这些都归因于人类错误.
结论:
- 在LMIC中报告的TR率与HIC中的TR率相似,这表明先进输血技术的影响有限.
- 在LMIC中,ABO不兼容仍然是一个重要问题,突出了对医疗保健人员加强培训的需要.
- 加强输血医学培训对于改善患者安全和减少LMIC中的错误至关重要.
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