相关实验视频

Updated: Jul 8, 2026

Detection of Disease-associated α-synuclein by Enhanced ELISA in the Brain of Transgenic Mice Overexpressing Human A53T Mutated α-synuclein
12:01

Detection of Disease-associated α-synuclein by Enhanced ELISA in the Brain of Transgenic Mice Overexpressing Human A53T Mutated α-synuclein

Published on: May 30, 2015

10.7K

在同核蛋白病变中基于CRISPR识别N-终端乙化

Eun-Jin Bae1, Seung-Jae Lee2

  • 1Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, South Korea; Neuroscience Research Institute, Seoul National University College of Medicine, Seoul, South Korea.

Trends in neurosciences
|March 29, 2024
PubMed
概括

研究人员发现,N终端乙化 (NTA) 可以稳定α-synuclein (α-synuclein). 针对NTA途径可能为涉及α-synuclein的疾病提供新的治疗策略.

关键词:
NatB NatB NatB NatB NatB NatB NatB NatB NatB NatB NatB NatB NatB NatB NatB NatB NatB NatB帕金森病是帕金森氏症的一种疾病.蛋白质酶体蛋白质组是什么蛋白质聚合蛋白质的聚合物α-synuclein 是一种同核蛋白.

更多相关视频

Sequential Extraction of Soluble and Insoluble Alpha-Synuclein from Parkinsonian Brains09:27

Sequential Extraction of Soluble and Insoluble Alpha-Synuclein from Parkinsonian Brains

Published on: January 5, 2016

17.3K
Characterizing Histone Post-translational Modification Alterations in Yeast Neurodegenerative Proteinopathy Models08:33

Characterizing Histone Post-translational Modification Alterations in Yeast Neurodegenerative Proteinopathy Models

Published on: March 24, 2019

7.5K

相关概念视频

Phase II Reactions: Acetylation Reactions01:24

Phase II Reactions: Acetylation Reactions

Acetylation, a phase II biotransformation reaction, introduces an acetyl group to drugs or their metabolites. Acetyltransferase enzymes facilitate this reaction, which resembles α-amino acid conjugation due to the addition of a functional group to the drug molecule.
The substrates for acetylation are typically drugs or their metabolites with an amino, sulfonamide, or hydrazine functional group. Acetylation can occur at several points in the drug molecule, including primary, secondary, and...