第三方病毒特异性T细胞输液后的二次骨髓移植损失:罕见并发症病例报告
Michael D Keller1,2,3, Stefan A Schattgen4, Shanmuganathan Chandrakasan5
1Center for Cancer and Immunology Research, Children's National Hospital, Washington, DC, USA.
Nature communications
|March 30, 2024
概括
病毒特异性T细胞 (VST) 对病毒感染有希望,但可能导致罕见的不良事件. 这一案例突出了婴儿在VST治疗后发生的严重反应,包括移植排斥和T细胞扩张.
科学领域:
- 免疫学 免疫学 免疫学
- 细胞疗法细胞疗法
- 移植 移植 移植 移植
背景情况:
- 病毒特异性T细胞 (VST) 为免疫功能低下患者的耐火性病毒感染提供了潜在的治疗方法.
- 虽然通常是安全的,但与VST治疗相关的罕见不良事件已被记录.
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