在患有1型糖尿病的儿科中,低于最佳的血糖控制的危险因素:一个横截面研究
Mobin Ghazaiean1,2, Behnam Najafi3, Daniel Zamanfar4
1Student Research Committee, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
Scientific reports
|March 30, 2024
概括
10-14岁的儿科患者和肥胖患者 (BMI ≥95百分位) 在1型糖尿病 (T1DM) 中面临低于最佳血糖控制的风险更高. 早期识别这些风险因素对于更好的长期管理至关重要.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 代谢障碍 代谢障碍 代谢障碍
- 糖尿病研究研究 糖尿病研究
背景情况:
- 1型糖尿病 (T1DM) 需要持续管理,以防止长期的并发症.
- 儿科T1DM患者的血糖控制受各种人口和临床因素的影响.
- 了解这些因素对于优化年轻人治疗策略至关重要.
研究的目的:
- 分析不同因素对T1DM儿科患者血糖控制的影响.
- 确定与低最佳血糖控制 (HbA1c ≥7.5%) 相关的特定风险因素.
- 为改善儿童和青少年T1DM的诊断和管理提供见解.
主要方法:
- 在2011-2020年期间治疗的204名儿科T1DM患者 (年龄<18岁) 的截面分析.
- 计算几率比率 (OR) 和95%置信区间 (CI) 以评估因子相关性.
- 多变量逻辑回归和克莱默的V用于确定非最佳控制的显著风险因素.
主要成果:
- 在75.49%的研究参与者中,观察到低于最佳的血糖控制.
- 年龄在10-14岁的患者显示,血糖控制低于最佳的可能性显著更高 (AOR 4.85).
- 肥胖 (BMI ≥95百分位) 也与低于最佳的血糖控制有显著的相关性 (克莱默的V = 0.21).
结论:
- 年龄 (10-14岁) 和肥胖 (BMI ≥95百分位) 是儿童T1DM中低于最佳血糖控制的重要危险因素.
- 这些发现强调了在治疗儿童T1DM时考虑年龄和体重状况的重要性.
- 对这些风险因素的早期识别和干预可以改善长期的血糖结果.
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