二手烟会增加患慢性阻塞性肺病的风险
Wen-Chi Su1, Huai-Lei Juan2,3, Jia-In Lee4
1Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Scientific reports
|March 30, 2024
概括
接触二手烟 (SHS) 显著增加了从不吸烟者患慢性阻塞性肺病 (COPD) 的风险. 即使是短暂的,定期的SHS暴露也会增加COPD风险,强调需要更严格的反吸烟政策.
科学领域:
- 肺部医学 肺部医学
- 环境健康 环境健康
- 流行病学 流行病学
背景情况:
- 吸烟是慢性阻塞性肺病 (COPD) 的主要危险因素.
- 关于二手烟 (SHS) 暴露与COPD发展之间的关联,存在有限的大规模证据.
- 暴露于SHS的非吸烟者面临潜在的呼吸系统健康风险.
研究的目的:
- 调查SHS暴露与从未吸烟者中患上COPD的风险之间的纵向关联.
- 量化与SHS暴露相关的发生性COPD风险.
- 探索SHS暴露时间和COPD风险之间的潜在剂量反应关系.
主要方法:
- 一项使用台湾生物库数据的纵向研究,包括6519名以前没有COPD的从未吸烟者.
- 参与者被分为SHS暴露和没有暴露的组.
- 考克斯的比例危险回归模型被用来评估COPD发展的相对风险 (RR),调整为混因素.
主要成果:
- 48个月后,暴露于SHS的组中有7%的患者患上了COPD,而未暴露组的患者只有4%.
- 暴露于SHS与发生慢性慢性肺炎的更高风险显著相关 (RR = 1.49; 95% CI 1.04-2.14; P = 0.031).
- 观察到一种剂量与反应的关系,每增加一小时的SHS暴露增加了COPD的可能性 (RR=1.03;95% CI 1.00-1.05;P=0.027).
结论:
- 接触二手烟是导致非吸烟者患上COPD的重要因素.
- 调查结果强调了公众对SHS危害的认识的重要性.
- 结果提供了证据,以支持制定全面的反吸烟政策,以减轻SHS风险.
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