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Updated: Jul 14, 2026

HPLC Coupled with Chemical Fingerprinting for Multi-Pattern Recognition for Identifying the Authenticity of Clematidis Armandii Caulis
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HPLC Coupled with Chemical Fingerprinting for Multi-Pattern Recognition for Identifying the Authenticity of Clematidis Armandii Caulis

Published on: November 11, 2022

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基于HPLC指纹与HPLC-Q-TOF-MS/MS方法相结合的Shexiang Tongxin降药片的质量评估

Ming Lin1,2, Chun-Ling Xu2, Hong-Ye Pan2,3,4

  • 1School of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Binwen Road, Binjiang District, Hangzhou 310053, People's Republic of China.

Journal of chromatographic science
|March 30, 2024
PubMed
概括

这项研究开发了一种全面的质量评估,用于谢祥通滴药 (STP),一种传统的中医治疗心血管疾病. 通过将HPLC指纹和质谱学结合起来,确定了100种生物活性化合物,从而实现了更好的质量控制.

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Drug Dissolution: Requirements and Profile Comparison01:14

Drug Dissolution: Requirements and Profile Comparison

The acceptance criteria for dissolution profile data are anchored in Q values, representing the percentage of drug dissolved within a specified period. This assessment unfolds in three stages:First Stage: The test passes if all six drug dosage units are equal to or greater than Q plus 5%; otherwise, the sample proceeds to the second stage.Second Stage: The average of twelve units must be equal to or greater than Q, with no unit falling below Q - 15% to pass; if not, it progresses to the final...