相关实验视频

Updated: Jun 29, 2025

Validated LC-MS/MS Panel for Quantifying 11 Drug-Resistant TB Medications in Small Hair Samples

Validated LC-MS/MS Panel for Quantifying 11 Drug-Resistant TB Medications in Small Hair Samples

Published on: May 19, 2020

改善多药耐药结核病患者服药的干预措施:一个范围审查

P Octaviani¹, Z Ikawati², N M Yasin³

¹Doctoral Program in Pharmacy, Faculty of Pharmacy, Gadjah Mada University, Yogyakarta, Indonesia.

The Medical journal of Malaysia

|March 30, 2024

概括

干预措施显著改善了对多抗结核病 (MDR-TB) 治疗的坚持,心理咨询是最有效的. 对个性化,具有成本效益的MDR-TB坚持策略需要进一步的研究.

科学领域:

公共卫生公共卫生
传染性疾病传染性疾病
药理学药理学是指药理学的学科.

背景情况:

对抗结核病 (TB) 药物的不服药助长了多药耐药结核病 (MDR-TB) 的传播,这是一个全球性健康威胁.
不良坚持延长治疗时间,增加不良事件,增加财务负担,需要有效的干预措施.

研究的目的:

进行旨在提高MDR-TB治疗患者的药物坚持性的干预措施的范围审查.
确定和综合现有研究,以改善患者遵守MDR-TB治疗的策略.

主要方法:

通过使用PubMed,Web of Science和Scopus的数据进行了观察性研究的范围审查.
数据合成使用Rayyan AI进行,遵循系统审查和元分析 (PRISMA) 准则的首选报告项目.

主要成果:

十一篇文章详细介绍了各种MDR-TB治疗坚持干预措施.
心理咨询/教育干预措施显示了最显著的遵守改善.
其他有效的干预措施包括药物事件提醒监视器 (MERM),视频直接观察疗法 (VDOT),财政支持,移动健康应用程序和DOTS/DOTS-Plus计划.
电子剂量监测 (EDM) 设备对MDR-TB患者坚持治疗的影响有限.

结论:

治疗MDR-TB的干预措施可以促进患者的康复.
虽然大多数研究显示了显著的改善,但存在异质性.
建议进行进一步的研究,以开发个性化,特定于环境的干预措施,并评估其成本效益.

更多相关视频

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

Published on: August 11, 2008

System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis

System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis

Published on: April 5, 2017

相关概念视频

Pulmonary Tuberculosis V

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...

Pulmonary Tuberculosis I

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...

Drug Therapy

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications

Pulmonary Tuberculosis IV

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...

Combined Effects of Drugs: Synergism

Combined Effects of Drugs: Synergism

Synergism is a useful mechanism where combining two or more drugs is more effective than each constituent used alone. Such combinations are also called supra-additive interactions. The drugs collectively enhance the final therapeutic effect by acting on different targets. Another advantage is that the low dose of each constituent drug is sufficient to achieve the desired effect. This helps reduce the duration of therapy and lower the adverse effects of these drugs.
Such synergistic combinations...

Dosage Regimen: Fixed Dose

Dosage Regimen: Fixed Dose

Fixed-dose regimens are a common approach to administer drugs to achieve and maintain desired levels of the drug in the body. In this dosing strategy, a specific amount of medication is given at regular intervals, often multiple times a day, to ensure a consistent drug concentration in the bloodstream.
Fixed-dose regimens can be used for various routes of administration, including intravenous (IV) injections and oral medications. For IV administration, a predetermined amount of the drug is...