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Updated: Jun 29, 2025

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组合性泛实时蛋白解析 (CURE-PROs):一个模块化平台,用于产生可逆的,自组装的双功能向降解器

Sarah F Giardina1, Elena Valdambrini1, Pradeep K Singh2

  • 1Department of Microbiology and Immunology, Weill Cornell Medicine, New York, New York 10065, United States.

Journal of medicinal chemistry
|March 30, 2024
PubMed
概括

组合性化实时蛋白解析 (CURE-PROs) 是一种新型的小分子降解剂,可以自组装. 这种新方法克服了解向金马 (PROTACs) 的局限性,以实现有效的向降解.

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