世界卫生组织2004年和世卫组织2017年甲状腺瘤分类的比较
Nirali Patel1, Rupali Bavikar, Yesha Parimalbhai Lad
1Department of pathology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth, Pimpri Pune, Maharashtra, India.
2017年世卫组织对甲状腺瘤的分类,包括边界类别,通过预防不足和过度诊断,改善了癌症管理. 这个新系统有助于准确评估甲状腺恶性瘤.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 病理学 病理学 病理学
背景情况:
- 2017年世界卫生组织 (WHO) 的甲状腺瘤分类引入了边界恶性瘤类别,并采用了对差分化癌症 (PDC) 的都灵标准.
- 以前的分类 (例如,世卫组织2004年) 缺乏对瘤具有不确定的恶性潜力的特定类别.
研究的目的:
- 为了比较世卫组织2004年和世卫组织2017年对甲状腺瘤的分类的诊断和临床影响.
- 评估修订后的分类对甲状腺癌管理的影响.
主要方法:
- 一项描述性,前性研究,涉及200名甲状腺瘤患者,持续了四年 (2018年7月 - 2022年6月).
- 数据分析使用了描述性统计数据.
- 患者在马哈拉施特拉州西部的一家三级医疗机构接受治疗.
主要成果:
- 世卫组织2017年分类将57.5%的恶性和42.5%的良性瘤根据2004年的系统重新分类为47.5%的恶性,27.5%的边缘和25%的良性类别.
- 乳头甲状腺癌仍然是最常见的恶性瘤 (32%),而卵泡腺瘤是最常见的良性瘤 (27%).
- 非侵入性毛囊性甲状腺新生体与乳头状核特征 (NIFTP) 是最常见的边缘性瘤 (17.5%).
结论:
- 在世卫组织2017年分类中包含边界类别显著提高了甲状腺癌管理.
- 经过修订的世卫组织分类有助于预防良性瘤的低诊断和恶性瘤的过度诊断.
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