在多发性骨髓瘤中发生骨髓瘤性膜溢出 - - 一种罕见的呈现形式
Ingale Yaminy Pradeep1, R Kulkarni Mayuri, S Patil Sourabh
1Department of Pathology, Dr. D.Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth, Pimpri, Pune, Maharashtra, India.
Journal of cancer research and therapeutics
|March 30, 2024
概括
在多发性骨髓瘤 (MM) 中,恶性多发性流很少见,这表明预后不佳. 早期诊断和治疗这种MM并发症对于潜在地改善患者的治疗结果至关重要.
科学领域:
- 血液学 血液学 血液学
- 在瘤学瘤学.
- 肺部病理学 肺部病理学
背景情况:
- 多发性骨髓瘤是一种血细胞恶性瘤,主要影响骨和骨髓.
- 在多发性骨髓瘤中,多发性液是罕见的,通常是由于同时存在的疾病引起的.
- 恶性骨髓瘤性外泄是非常罕见的并发症,在<1%的患者中见到.
研究的目的:
- 在复发的多发性骨髓瘤患者中报告一种罕见的双边骨髓瘤性多发性骨髓漏液病例.
- 为了突出与骨髓瘤性膜溢出相关的不良预后.
- 强调早期诊断和治疗启动的重要性.
主要方法:
- 一个41岁多发性骨髓瘤患者的病例报告.
- 进行的治疗:循环胺,博尔特佐米布和德克萨梅他化疗.
- 临床过程监测和结果评估.
主要成果:
- 患者在疾病复发期间出现了双侧膜溢出.
- 观察到对化疗的初始阳性反应.
- 尽管接受了治疗,但患者的病情恶化,导致一个月内死亡.
结论:
- 骨髓瘤性外流意味着多发性骨髓瘤患者的预后很严重.
- 及时诊断和及时的治疗干预对于管理这种罕见的并发症至关重要.
- 早期考虑骨髓瘤性外泄可能有助于改善患者的存活率.
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