长期多中心监测Enterobactercloacae复合体 - - 临床前景
M D Mauritz1, B Claus2, J Forster3
1Department of General Pediatrics and Adolescent Medicine, Children's and Adolescents' Hospital, Datteln, Germany; Department of Children's Pain Therapy and Pediatric Palliative Care, Faculty of Health, School of Medicine, Witten/Herdecke University, Witten, Germany.
The Journal of hospital infection
|March 30, 2024
概括
肠杆菌菌综合体 (ECCO) 感染在重症监护和瘤病房中很常见,特别是在老年男性中. 对碳烯的耐药性仍然很低,这表明目前的治疗方法对这些肠道细菌有效.
科学领域:
- 医学微生物学 医学微生物学
- 传染性疾病 传染性疾病
- 医疗卫生流行病学 医疗卫生流行病学
背景情况:
- 肠道细菌cloacae复合体 (ECCO) 导致各种感染,包括严重的血液感染.
- 在医疗保健相关的感染中,ECCO 是一个重要的病原体,特别是在重症监护机构.
研究的目的:
- 详细介绍德国三级医院ECCO的流行病学和耐药性模式.
- 通过Enterobacter Cloacae COMplex PASsive Surveillance (EC-COMPASS) 的研究,提供ECCO的多中心概述.
主要方法:
- 分析了2020年1月至2022年12月期间来自14311名患者的31,193个ECCO培养阳性结果.
- 采用Hybase®实验室数据从四家德国三级医院的哨兵集群中收集的数据.
主要成果:
- 在男性患者中,ECCO感染的发病率更高,抽样和尿液是常见的来源.
- 侵袭性感染集中在瘤和重症监护病房,每年细菌病率稳定.
- 在ECCO分离物中,碳烯耐药性始终很低.
结论:
- 埃科感染不成比例地影响瘤和重症监护病房的老年男性.
- 该EC-COMPASS研究为德国医疗保健中的ECCO感染提供了有价值的临床见解.
- 建议早期检测和有针对性的策略来管理脆弱的患者群体.
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