饮用水系统中新出现的有机污染物:人类摄入量,新出现的健康风险以及未来的研究方向
Jerikias Marumure1, Tinoziva T Simbanegavi2, Zakio Makuvara1
1Department of Physics, Geography and Environmental Science, School of Natural Sciences, Great Zimbabwe University, Masvingo, Zimbabwe; Department of Life and Consumer Sciences, School of Agriculture and Life Sciences, College of Agriculture and Environmental Sciences, University of South Africa, South Africa.
Chemosphere
|March 30, 2024
概括
饮用水系统 (DWS) 中新出现的有机污染物 (EOC) 对健康构成重大风险,特别是在低收入地区. 本综述强调了EOC的人类摄入量,毒动力学和毒动力学,强调了长期和相互作用的健康影响.
科学领域:
- 环境科学 环境科学
- 毒理学 毒理学 毒理学
- 公共卫生 公共卫生
背景情况:
- 新兴有机污染物 (EOC) 在饮用水系统 (DWS) 中越来越多地被检测到.
- 以前的审查主要集中在EOC检测,行为和去除上,对人类暴露途径和健康风险的关注有限.
- 了解EOC的毒动力学和毒动力学对于评估人类健康影响至关重要.
研究的目的:
- 介绍最近在理解DWS中与EOC相关的人类摄入量和健康风险方面的进展.
- 分析全球关于河流中制药污染及其对人类摄入的影响的数据.
- 批评EOCs新出现的健康危害,并确定未来的研究需求.
主要方法:
- 对DWS中EOCs现有文献的审查,重点关注人类暴露,摄入量和健康风险.
- 对不同收入地区河流中药物度的全球数据的分析.
- 对EOC的毒动力学,毒动力学和新出现的健康危害的批评.
主要成果:
- DWS 含有广泛的 EOC,具有多种暴露途径,包括摄入,吸入和皮肤接触.
- 与高收入地区相比,在南美,亚洲,非洲和东欧的河流中,制药污染明显更高.
- 人类通过河水摄入的药品在低收入和中等收入地区更高,婴儿是受影响最严重的人群.
结论:
- DWS中的EOCs对人类健康构成重大风险,包括长期,代际和相互作用的影响.
- 健康和疾病的发育起源 (DOHaD) 假设与理解EOC对健康的影响有关.
- 需要进一步的研究来解决DWS中EOC所带来的复杂健康危害.
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