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Updated: Jul 15, 2026

Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells
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在实验室中,从血液细胞的原始细胞中产生来自小鼠骨髓细胞的抑制细胞

Lorraine M Hernandez-Delgado1, Andrea Laboy-Figueroa1, Alondra Lopez-Velazquez1

  • 1Department of Biology, University of Puerto Rico, Humacao, Puerto Rico.

Methods in cell biology
|March 30, 2024
PubMed
概括

研究人员开发了一种方法,以在体外产生免疫抑制的髓质衍生抑制细胞 (MDSC). 该协议使用造血原生细胞 (HPC) 和瘤超级细胞来研究与癌症相关的免疫抑制.

关键词:
骨髓细胞是骨髓中的细胞.血液形成的原始细胞是血造细胞.在体外 (in vitro) 的情况下.来自骨髓细胞的抑制细胞.瘤扩展性超性超性.

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Common myeloid progenitors (CMPs) are oligopotent cells that can differentiate into granulocytes and macrophages. Granulocytes and macrophages are essential for protecting the body against bacterial, viral, or fungal infections. They migrate from the bone marrow into the circulating blood to reach specific tissue sites where they differentiate and help in immune surveillance. However, they survive only for a few days and must be continuously made available to the organism to maintain a robust...