在正常听力情况下的耳中皮下听觉系统:从电生理学角度的见解
Hasan Colak1, Eser Sendesen2, Meral Didem Turkyilmaz2
1Biosciences Institute, Newcastle University, Newcastle Upon Tyne, UK. h.colak2@newcastle.ac.uk.
概括
患有耳的人表现出皮下听力处理受损,包括声音编码缺陷和神经噪声增加. 这些发现与尽管正常听力值,但语音噪音感知较差的相关.
科学领域:
- 神经科学是一个神经科学.
- 听觉神经科学 听觉神经科学
- 临床听力学 临床听力学
背景情况:
- 人们对声机制的了解很少.
- 皮下听觉系统在声的感知中发挥着作用.
研究的目的:
- 在耳中使用电生理学研究皮质下听觉系统.
- 评估 tinnitus 患者的语音与噪音 (SiN) 感知.
- 确定耳是否与SiN缺陷有关,尽管听力正常.
主要方法:
- 电生理学记录:听觉脑干反应 (ABR) 和语音引起的频率随访反应 (sFFR).
- 参与者:42个正常听力的人 (22个患有慢性主观耳,20个对照).
- 使用矩阵测试评估SiN感知.
主要成果:
- 在耳组中,sFFR (声音偏移编码) 的长期O-峰值.
- tinnitus 患者的非刺激唤起活动增加.
- 降低波I振幅和延长的延迟在ABR的耳声组.
- 与对照人群相比, tinnitus 患者的 SiN 感知较差.
结论:
- 损坏的音响偏移编码表明在耳中抑制机制的缺陷.
- 在耳组中观察到皮下水平的神经噪声增加.
- 耳可能导致SiN缺陷,即使在正常的音频图.
- 缺乏抑制和增加的神经噪声是导致耳的潜在因素.
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