在anammox工艺中强烈抑制银纳米颗粒对抗生素耐药性
Hongwei Sun1, Huanhuan Chang2, Yuliang Zhu3
1School of Environmental and Material Engineering, Yantai University, Yantai, Shandong 264005, China.
Journal of hazardous materials
|March 31, 2024
概括
银纳米粒子 (AgNPs) 对泥性能和循环产生负面影响. 然而,AgNP有效地降低了抗生素耐药性基因 (ARG),并抑制了它们在工程生态系统中的传播.
科学领域:
- 环境微生物学 环境微生物学
- 纳米技术纳米技术
- 废水处理 废水处理
背景情况:
- 在废水处理中,Anammox工艺对于去除至关重要.
- 银纳米粒子 (AgNPs) 的使用越来越多,但其生态影响尚未完全理解.
- 了解AgNP对微生物群落和抗生素耐药性的影响对于工程生态系统至关重要.
研究的目的:
- 为了研究AgNPs对anammox污泥性能的影响.
- 分析微生物社区结构和功能中的变化.
- 评估AgNP对抗生素耐药性基因 (ARG) 和水平基因转移 (HGT) 的影响.
主要方法:
- 在200个循环中,长期暴露于不同度的AgNPs (0-2.5 mg/L) 的anammox花泥.
- 监测去除效率和关键的阿纳莫克斯酶 (hzsA,nirK).
- 使用结构方程建模 (SEM) 分析微生物社区结构,ARG丰富度和移动遗传元素 (MGE) 介导的HGT.
主要成果:
- 随着AgNP度的增加,Anammox的性能显著下降.
- 占主导地位的阿纳莫克斯细菌的相对丰富 (Ca. 昆尼尼亚) 和相关酶的增加.
- 在较高的AgNP度 (1.5-2.5 mg/L) 中,ARG的丰度显著下降,而AgNP则抑制了ARG的MGE介导的HGT.
结论:
- AgNP抑制了由亚纳摩克斯驱动的循环,并改变了花污泥中的微生物群落结构.
- 农业农产品计划有效地防止ARG和相关HGT的传播.
- 这项研究提供了纳米粒子和工程系统中抗性元素的生态作用的见解.
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