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Updated: Jun 29, 2025

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MAPK15通过调节NRF2活性和下游目标基因的表达来控制细胞对氧化应激的反应

Lorenzo Franci1, Giulia Vallini2, Franca Maria Bertolino3

  • 1Istituto di Fisiologia Clinica (IFC), Consiglio Nazionale Delle Ricerche (CNR), Siena, Italy; Core Research Laboratory (CRL), Istituto per lo Studio, la Prevenzione e la Rete Oncologica (ISPRO), Siena, Italy.

Redox biology
|March 31, 2024
PubMed
概括

基激活蛋白激酶15 (MAPK15) 通过激活NRF2通路来增强细胞对氧化应激的防御能力. 这一发现为与活性氧物种 (ROS) 相关的疾病提供了新的治疗点.

关键词:
细胞信号传递 细胞信号传递慢性呼吸道疾病 慢性呼吸道疾病香烟烟雾的烟雾是什么意思基因表达 基因表达 基因表达肺癌是一种肺癌.它们是MAP激酶.

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