通过合作开发核心成果集来增加采用率:在OMERACT 2023上吸取经验教训
Beverley Shea1, Jordi Pardo Pardo2, Shawna Grosskleg3
1Ottawa Hospital Research Institute, Clinical Epidemiology Program, University of Ottawa, 501 Smyth Road, Ottawa, ON, K1H 8L6, Canada; Bruyère Research Institute, Ottawa, Canada; University of Ottawa, School of Epidemiology and Public Health, Faculty of Medicine, Ottawa, Canada.
Seminars in arthritis and rheumatism
|March 31, 2024
概括
加强核心成果集 (COS) 的采用,需要与合作者建立强有力的伙伴关系,并满足他们的需求. 患者参与和意识是改善临床研究中COS影响的关键.
科学领域:
- 卫生研究方法论 卫生研究方法论
- 临床试验设计 临床试验设计
- 患者为中心的结果.
背景情况:
- 核心成果集 (COS) 对于标准化研究成果至关重要.
- 之前的研究表明,对于个别核心结果的采用率是可变的.
- 采用COS的障碍包括缺乏验证的工具和利益相关者的参与不足.
研究的目的:
- 强调加强核心成果集 (COS) 采用的重要性.
- 强调与合作伙伴建立伙伴关系,并在COS开发中解决他们的需求.
- 探索改善COS在临床研究中的相关性和影响的策略.
主要方法:
- 使用了一个类似游戏节目结构的模拟会话.
- 八个合作小组讨论了COS在各自领域的重要性.
- 进行了对已识别的COS采用障碍的分析.
主要成果:
- 观察到各个核心结果的采用率存在差异.
- 确定的主要障碍包括缺乏验证的仪器建议,患者和合作者的参与不足,以及对COS的认识不足.
- 优先考虑患者和多样化的合作伙伴在COS开发中的纳入是必不可少的.
结论:
- COS的发展必须优先考虑患者和多样化的合作伙伴的包容性.
- 未来的研究应该探索更广泛的COS实施和影响因素.
- 扩展COS开发以推验证的工具,并接受患者的领导,对于推进COS影响至关重要.
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