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免疫检查点受体LAG3:癌症免疫治疗的结构,功能和点

Roy A Mariuzza1, Salman Shahid1, Sharanbasappa S Karade1

  • 1W.M. Keck Laboratory for Structural Biology, University of Maryland Institute for Bioscience and Biotechnology Research, Rockville, Maryland, USA; Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland, USA.

The Journal of biological chemistry
|March 31, 2024
PubMed
概括

淋巴细胞激活基因3 (LAG3) 是一种免疫检查点受体,在癌症中阻断T细胞功能. 新的研究探索了LAG3的分子相互作用和治疗抗体,针对癌症免疫疗法和自身免疫性疾病.

关键词:
FGL1 FGL1 FGL1 FGL1 FGL1 FGL1 FGL1 FGL1 FGL1 FGL1 FGL1 FGL1在LAG3中.在MHC中,MHC是最重要的.免疫检查点检查点结构的结构结构的结构.

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