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Updated: Jun 29, 2025

Using RNA-interference to Investigate the Innate Immune Response in Mouse Macrophages
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巨细胞的组织特异性转录编程控制了针对多个功能途径的microRNA转录组

Magdalena A Czubala1, Robert H Jenkins1, Mark Gurney1

  • 1Systems Immunity Research Institute and Division of Infection and Immunity, Cardiff University, Cardiff, UK.

The Journal of biological chemistry
|March 31, 2024
PubMed
概括

转录因子GATA6对于编程腹膜组织居民巨细胞 (pMΦ) 至关重要. 其缺乏会显著改变microRNA的表达,影响免疫反应和细胞循环调节在这些专门的巨细胞.

关键词:
GATA转录因子的转录因子恒常状态 (homeostasis) 是一种平衡状态.巨细胞是一个巨细胞.微RNA (miRNA) 是一种微型RNA.翻译学 翻译学 翻译学 翻译学

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