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用Corvis ST测量的近视和视的角膜生物力学特征:一个元分析

Min-Xin Liu¹, Ke-Yao Zhu², Dan-Lin Li¹

¹School of Public Health (M.X.L., D.L.L., X.X.D., C.W.P.), Suzhou Medical College of Soochow University, Suzhou, China.

American journal of ophthalmology

|March 31, 2024

概括

角质生物力学在近视,特别是高近视方面有所不同. 高近视显示较慢的第一次平整,更快的第二次平整,并增加了变形幅度,表明较高的弹性和粘度比非高近视.

科学领域:

眼科医生眼科眼科
生物机械工程生物机械工程
视觉科学视觉科学视觉科学

背景情况:

近视是一种普遍的折射误差,与角膜结构和生物力学变化有关.
准确评估角膜生物力学对于理解近视的进展和管理眼睛健康至关重要.
科尔维斯ST (角膜粘性机械表面拓仪) 是一种用于测量角膜生物机械性质的设备.

研究的目的:

系统地审查和对评估角膜生物力学差异的研究进行元分析,这些差异是通过Corvis ST测量在不同程度近视和视的个体中.
确定特定的生物力学参数,以区分近视眼和视眼.
与非高近视相比,高近视的独特生物力学特征.

主要方法:

在PubMed,Embase和Web of Science数据库中进行了系统的文献搜索.
包括比较使用Corvis ST在近视和近视障碍患者中的角膜生物力学研究.
进行了元分析,以计算各种生物力学参数的加权平均差异和95%置信区间.

主要成果:

包括11项研究,涉及1947个近视和621个近视,以及443个高近视和449个非高近视.
与近视眼相比,近视眼在第一次平面化时 (A1t) 的时间明显更长,在第二次平面化时 (A2L) 的长度更低.
高近视者表现出明显更大的A1t,第二次平面化时的速度 (A2v),变形幅度 (HC-DA) 和峰值距离 (HC-PD),以及第二次平面化时的时间减少 (A2t) 和最高度半径 (HC-R).

结论:

角膜生物力学在近视患者中明显不同,在高近视患者中观察到显著的区别.
高近视角膜在Corvis ST测试期间显示变化的变形模式,包括较慢的初始变形和更快的后续变形.
这些发现表明,高近视与角膜弹性和粘度的增加有关,由更大的变形幅度表明.

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