在新生儿重症监护病房使用低剂量多巴胺
Mallory A Prideaux1, Ronnie Guillet1
1Division of Neonatology, Golisano Children's Hospital, University of Rochester, Rochester, NY.
NeoReviews
|March 31, 2024
概括
低剂量的多巴胺被广泛用于新生儿急性损伤 (AKI),尽管缺乏证据表明它有好处,但却会引起不良影响,特别是在早产婴儿身上. 本审查审查了当前关于其在新生儿中使用的知识.
科学领域:
- 新生儿医学 新生儿医学
- 药理学 药理学是指药理学的学科.
- 腎臟病學 (nephrology) 是一種醫學專業.
背景情况:
- 多巴胺几十年来一直用于治疗低血压,理论上可以预防儿科患者的急性损伤 (AKI).
- 脏多巴胺受体的激活会增加尿液输出,但缺乏证据表明低剂量的多巴胺可以预防AKI,透析或死亡.
- 多巴胺使用与不良影响有关,特别是在早产婴儿中.
结论:
- 目前的证据不支持在新生儿中常规使用低剂量多巴胺来预防或治疗AKI.
- 新生儿科医生应该重新考虑使用低剂量的多巴胺,因为缺乏证明的益处和潜在的危害.
- 需要进一步的研究来确定多巴胺在新生儿病学中的真正作用,如果有的话.
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