下肢骨质整合后的感染:病原体,管理和结果的单一中心回顾性评估
Grant G Black1, Anna M Vaeth1, Makayla Kochheiser1
1From the Division of Plastic and Reconstructive Surgery, Weill Cornell Medicine.
Annals of plastic surgery
|April 1, 2024
概括
对于下肢截肢者来说,骨质整合 (OI) 是有效的,感染很少需要手术. 大多数感染都是用抗生素治疗的,并且植入物挽救率很高,这使得OI成为一种安全的治疗选择.
科学领域:
- 生物医学工程 生物医学工程
- 整形外科手术 整形外科手术
- 传染性疾病 传染性疾病
背景情况:
- 骨整合 (OI) 为下肢截肢者提供了传统假肢的替代方案.
- 在OI植入物中的口腔带有细菌感染的风险,报告的病例高达66%.
研究的目的:
- 在下肢截肢者中对骨整合植入物进行感染管理策略的分类.
- 分析长期结果并最大限度地提高感染后的植入物挽救率.
主要方法:
- 在2017年至2022年期间接受了下肢OI的102名患者的回顾性分析.
- 根据感染的存在和严重程度对患者进行分层.
- 使用奇平方和t测试 (alpha = 0.05) 的统计分析.
主要成果:
- 骨髓炎更常见的是多微生物感染,而不是软组织感染 (71%对23%).
- 胃感染主要用口服抗生素治疗 (96%).
- 感染后的整体植入物挽救率为96%.
结论:
- 骨整合后的感染通常可以用抗生素治疗,很少需要手术干预.
- 由于感染而导致的扩张是不常见的,并且重新植入是可行的.
- 骨整合被证实是下肢截肢者安全有效的治疗方法.
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