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Updated: Jun 29, 2025

Microwave-Assisted Preparation of 1-Aryl-1H-pyrazole-5-amines
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Microwave-Assisted Preparation of 1-Aryl-1H-pyrazole-5-amines

Published on: June 23, 2019

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编程异循环合成使用Halomucononitriles作为Pyridinimine前体

Adam J Zahara1, Brandon E Haines2, Sidney M Wilkerson-Hill1

  • 1Department of Chemistry, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.

Organic letters
|April 1, 2024
PubMed
概括

这项研究提出了一种两步方法,从原始氨基中合成药物构建基,如imidazo[1,2-a]pyridines和7-alkyl azaindoles. 这种新的方法利用氨基烯酸试剂进行高效的循环和随后的交叉合或C-H功能化反应.

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