在内镜鼻手术后重新开始抗血栓治疗:系统性审查
Trinithas Boyi1, Rhys L Richmond1, Darpan Kayastha1
1Department of Surgery, Division of Otolaryngology-Head and Neck Surgery, Yale School of Medicine, New Haven, CT, USA.
The Annals of otology, rhinology, and laryngology
|April 1, 2024
概括
在内镜外科手术 (ESS) 后恢复抗血栓治疗缺乏明确的指导方针. 这次系统性审查发现,有关ESS后安全恢复抗凝固剂和抗血小板剂的文献中存在重大差距.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 心脏病学 心脏病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 在内镜外科手术 (ESS) 之前暂停抗血栓治疗 (抗凝固剂和抗血小板剂),以尽量减少出血风险.
- 目前的临床实践缺乏关于在ESS后安全恢复这些关键药物的指导方针.
研究的目的:
- 系统地审查现有的文献,以建议在ESS后恢复抗血栓治疗的时间.
- 确定有关ESS后抗血栓管理的证据缺口.
主要方法:
- 在多个数据库 (PubMed,Embase,Web of Science等) 进行了全面的系统文献搜索. 按照PRISMA的指导方针进行.
- 包含的研究被两个独立的审查员选,重点是确定ESS后恢复抗血栓治疗的建议.
主要成果:
- 在确定的104个独特文章中,只有6个符合分析的纳入标准.
- 审查的文献主要集中在ESS之前暂停抗血栓治疗,关于恢复时间的讨论有限 (3篇文章).
- 在ESS后恢复抗血栓剂的建议被发现是混合的和不一致的.
结论:
- 在科学文献中,关于在ESS之后恢复抗血栓治疗的科学文献非常少.
- 迫切需要制定基于证据的指导方针,以指导耳鼻喉科医生管理恢复抗血栓治疗,从而影响患者的发病率.
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