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在2型糖尿病中甲状腺功能障碍的患病率
1Dr Mohammad Rakibul Islam, Emergency Medical Officer, Mymensingh Medical College Hospital, Mymensingh, Bangladesh;
Mymensingh medical journal : MMJ
|April 1, 2024
概括
甲状腺功能障碍在2型糖尿病 (T2DM) 患者中比在非糖尿病患者中更常见. 建议对T2DM患者进行甲状腺功能障碍,特别是甲状腺功能低下的查,特别是那些50岁以上或患有高空腹血葡萄糖的人.
科学领域:
- 内分泌学 在内分泌学.
- 代谢障碍 代谢障碍 代谢障碍
- 甲状腺学 甲状腺学
背景情况:
- 没有控制的糖尿病可以改变甲状腺激素水平.
- 2型糖尿病患者 (T2DM) 患甲状腺疾病的患病率更高.
- 查甲状腺功能障碍 (TD) 在T2DM管理中至关重要.
研究的目的:
- 为了比较T2DM患者中甲状腺功能障碍的患病率与非糖尿病对照.
- 在T2DM患者中识别与甲状腺功能障碍相关的危险因素.
主要方法:
- 一项涉及100名T2DM患者和100名非糖尿病对照者的横截面比较研究.
- 评估禁食血葡萄糖 (FPG),血清自由三铁素 (FT3),自由甲状腺素 (FT4) 和甲状腺刺激激素 (TSH) 的水平.
- 分析包括后勤回归来确定关联.
主要成果:
- 甲状腺功能障碍在T2DM患者 (15.0%) 与对照组 (5.0%) (p=0.018) 相比明显更为普遍.
- 亚临床甲状腺功能低下症和甲状腺功能低下症是两组中最常见的TD类型.
- 在40-60岁,超重/肥胖个体以及具有较高FPG水平的个体中,TD更频繁. 年龄>50岁和高FPG与TD有显著的关联.
结论:
- 甲状腺功能障碍在T2DM患者中比在一般人群中更为普遍.
- 建议对T2DM患者进行常规的TD查,包括TSH和FT4测量.
- 年龄和FPG升高是T2DM患者TD的重要危险因素.
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