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免疫推迟做法围绕着先天性心脏手术
Dana B Gal1,2, John D Cleveland2,3, Jeffrey E Vergales4
1Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Cardiology in the young
|April 1, 2024
概括
大多数儿科中心在先天性心脏手术周围推迟了常规儿童免疫接种,增加了脆弱儿童的风险. 目前的做法有很大差异,可能不必要,这就需要进一步研究外科手术期间免疫接种的安全性和有效性.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 免疫学 免疫学 免疫学
- 公共卫生 公共卫生
背景情况:
- 在先天性心脏手术 (CHD) 周围进行外科手术期间的免疫接种是有争议的.
- 延迟免疫接种增加了医学上脆弱的儿童患有心血管疾病的疫苗可预防疾病的风险.
- 有限的研究表明,术后免疫可能是安全和有效的.
研究的目的:
- 在进行先天性心脏手术的中心调查当前的外科手术前免疫接种实践.
- 确定免疫推迟政策的变化和趋势.
- 评估与当前做法相关的潜在风险.
主要方法:
- 对儿科急性护理心脏病协作协会成员中心的调查.
- 使用描述性统计数据分析调查答案.
主要成果:
- 35/46 (76%) 的中心作出回应,显示了实践的显著差异.
- 大多数中心 (66%) 将免疫接种推迟到手术前,89%推迟到手术后.
- 手术后的延期通常与心肺绕道相关,持续时间可变,特定疫苗的例外.
结论:
- 大多数中心在先天性心脏手术前后推迟常规儿童免疫接种.
- 这些不同的延期做法对患者构成风险,可能是不合理的.
- 需要进一步的研究来了解免疫学影响和免疫接种的最佳时间在这个人群中.
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