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在患有视神经低成形和七眼视垂体形症的儿童中视觉敏度结果

Michael S Salman¹, Shakhawat Hossain², Elizabeth Carson³

¹Section of Pediatric Neurology, Department of Pediatrics and Child Health, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.

Pediatric neurology

|April 1, 2024

概括

在视神经缺血症 (ONH) /七视垂体缺血症 (SOD) 患者中,最佳校正的视敏度 (BCVA) 随着时间的推移显示出统计学上显著但临床上较小的变化. 这些发现表明ONH/SOD是非进展性神经发育障碍.

科学领域:

眼科医生眼科眼科
神经科学是一个神经科学.
发展生物学发展生物学

背景情况:

视神经缺血症 (ONH) 和阴视垂体缺血症 (SOD) 是一种影响视觉发育的先天性疾病.
了解ONH/SOD患者的长期视觉结果对于管理至关重要.
以前的假设表明,这些患者的视力敏度保持稳定.

研究的目的:

在被诊断为ONH/SOD的患者中,随着时间的推移,研究最佳校正视敏度 (BCVA) 的变化.
为了确定ONH/SOD患者的BCVA是否随着年龄的增长而发生显著变化.

主要方法:

已确认ONH/SOD诊断的患者的回顾性图表审查.
提取人口统计和临床眼科数据.
在临床访问中使用最小分辨率角 (logMAR) 的对数对BCVA进行定量分析.

主要成果:

分析了102名患者 (56名男性) 的队列,平均随访时间为4.5年.
在最受影响的眼睛中,BCVA显示了统计学上显著的轻微恶化 (0.056 logMAR/年).
在较小或同样受到影响的眼睛 (0.014 logMAR/年) 中观察到BCVA的统计学上显著的轻微改善.

结论:

虽然在统计学上显著,但BCVA观察到的变化在临床上是轻微的,可能小于一个斯内伦图表线.
这些发现支持将ONH/SOD归类为非进展性神经发育障碍.
观察到的视觉变化可能归因于盲视,发育成熟或随着年龄的增长而提高的评估可靠性.

关键词:

视神经的低成形是什么?结果结果的结果.儿科儿科儿科视力敏度视力敏度视力敏度

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