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利用多主题数据来赋予定量系统药理学在免疫瘤学中的权力

Theinmozhi Arulraj1, Hanwen Wang1, Alberto Ippolito1

  • 1Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Briefings in bioinformatics
|April 1, 2024
PubMed
概括

从多学科数据中利用生物信息学可以为定量系统药理学 (QSP) 模型提供信息. 这种方法有助于理解瘤微环境 (TME) 动态,并优化癌症免疫治疗策略.

关键词:
生物信息学是一种生物信息学.免疫疗法 免疫疗法俄米克斯 (omicsics) 是一个电子产品.精确瘤学 精确瘤学定量系统药理学 药理学

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Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...
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