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一种罕见的多关节炎 (PAN) 呈现
Joud Enabi1, Kejal Shah1, Hema Kondakindi1
1Internal Medicine, Texas Tech University Health Sciences Center, Odessa, USA.
Cureus
|April 1, 2024
概括
这一病例突出显示了一种罕见的 Polyarteritis Nodosa (PAN) 呈现,由于动脉动脉瘤破裂而导致急性腹部. 迅速诊断和治疗动脉栓塞和免疫抑制 (cyclophosphamide和类固醇) 导致一个成功的结果.
科学领域:
- 血管医学 血管医学
- 类风湿病学 类风湿病学
- 胃肠病学 胃肠病学
背景情况:
- 多关节炎 (PAN) 是一种系统性血管炎,影响中等大小的动脉,其特征是死性炎症.
- PAN可以导致动脉衰弱,动脉瘤和破裂,呈现出各种不同的临床表现.
- 连接组织疾病,如PAN需要及时诊断和管理,以防止危及生命的并发症.
研究的目的:
- 报告一种罕见的多关节炎 (Nodosa) 病例,由于脏动脉动脉瘤破裂而呈现为急性腹部.
- 讨论与PAN相关的内脏动脉动脉瘤的诊断挑战和管理策略.
- 强调在动脉瘤破裂的情况下迅速干预的重要性.
主要方法:
- 一个48岁男性的病例研究,患有急性缺氧呼吸衰竭和随后的急性腹部.
- 诊断工作包括实验室检查,腹部CT血管造影,并排除感染性/其他原因.
- 治疗包括干预性放射学 (动脉栓塞) 和免疫抑制疗法 (cyclophosphamide和皮质类固醇).
主要成果:
- 腹部CT显示动脉动脉瘤与显著的血,表明破裂.
- 动脉栓塞稳定了患者的血红蛋白水平.
- 该患者因多关节炎 (Polyarteritis Nodosa) 接受了循环胺和皮质类固醇治疗,反应良好.
结论:
- 多关节炎 (Nodosa) 可以异常表现为急性腹部紧急情况,如动脉瘤破裂.
- 涉及干预性放射学和风湿病学的多学科方法对于管理如此复杂的病例至关重要.
- 使用环胺和类固醇的联合治疗在治疗严重的多性炎中是有效的.
相关概念视频
Acute Pancreatitis I: Introduction
Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Chronic Pancreatitis I: Introduction
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Peripheral Artery Disease I: Introduction
Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
Acute Pancreatitis I: Introduction
Acute pancreatitis is the sudden inflammation of the pancreas caused by the early activation of digestive enzymes, leading to the autodigestion of pancreatic tissue. This results in local inflammation and, in severe cases, systemic complications.EtiologyUnderstanding the underlying causes is crucial, as identifying the etiology guides treatment and anticipates complications. Acute pancreatitis can be triggered by various factors, typically grouped into the following clinical categories.Biliary...
Chronic Pancreatitis I: Introduction
Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80% of...

