在患有类风湿性疾病的患者中进行COVID-19预防,诊断和治疗. 波兰专家小组发表了意见
Brygida Kwiatkowska1, Magdalena Krajewska-Włodarczyk2, Bogdan Batko3
1Early Arthritis Clinic, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland.
Reumatologia
|April 1, 2024
概括
患有风湿和肌肉骨疾病 (RMDs) 的成年人面临更高的SARS-CoV-2感染风险,原因是免疫因素和并发症. 关于免疫接种,诊断和抗病毒治疗的最新指南对于在这个脆弱人群中管理COVID-19至关重要.
科学领域:
- 免疫学 免疫学 免疫学
- 类风湿病学 类风湿病学
- 传染性疾病 传染性疾病
背景情况:
- 严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 变种对脆弱人群构成重大风险,特别是患有风湿和肌肉骨疾病 (RMD) 的成年人.
- 患有RMD的个体由于慢性炎症,免疫抑制,晚年,多病症和怀孕,患有严重COVID-19的风险增加.
- 后COVID-19的表现在RMD患者中更为普遍,与免疫失调,病毒持久性和遗传因素有关.
研究的目的:
- 提供有关RMD患者SARS-CoV-2感染的最佳管理的最新指导.
- 为应对RMD群体在COVID-19方面面临的独特挑战和增加的风险.
- 在这个特定的患者群体中审查当前免疫,诊断和抗病毒治疗的策略.
主要方法:
- 本综述综合了有关RMD患者COVID-19的当前文献和专家建议.
- 它检查了致病遗传机制,有助于增加易感性和严重性.
- 关于疫苗接种,诊断和治疗方案的指导是根据现有证据得出的.
主要成果:
- 建议RMD患者接种COVID-19疫苗,因为益处超过风险.
- 患有RMD的患者患重病和COVID-19后疾病的风险更高.
- 早期诊断和抗病毒治疗对于缓解RMD群体的结果至关重要.
结论:
- 正式的指导和专门的协议对于在RMD患者中管理COVID-19至关重要.
- 医疗保健提供者必须对感染症状保持警,并促进及时诊断和治疗.
- 对于风湿病学家来说,积极的教育和意识对于在患者中有效管理COVID-19至关重要.
相关概念视频
The JAK-STAT Signaling Pathway
8.9K
Several cytokine receptors have tightly bound Janus kinase or JAK proteins attached at their cytosolic tail. Small signaling molecules such as cytokines, growth hormones, or prolactins bind to the cytokine receptors and initiate their dimerization. The dimerization brings the cytosolic JAKs together that trans-phosphorylate and activates each other. The activated JAKs now phosphorylate cytosolic tails of the cytokine receptors, which serve as binding sites for adaptor proteins such as SH2...
8.9K
Pneumonia III: Complications and Assessment
206
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
206
Drugs Used in Lower Respiratory Disorders: Overview
437
Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
437
Pulmonary Tuberculosis V
179
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
179
Acute Pharyngitis
633
Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
633
Pneumonia IV: Management
324
The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
324


